Description

• General description: High purity Fmoc-protected amino acid for research and process production of peptides, with very low levels of dipeptide, free-amino acids and acetic acid impurities. Standard building block for introduction of serine amino-acid residues by Fmoc SPPS Associated Protocols and Technical ArticlesFmoc-amino acids for Peptide ProductionCleavage and Deprotection Protocols for Fmoc SPPS
• Application: Stereoselective polymer-supported synthesis of morpholine-and thiomorpholine-3-carboxylic acid derivatives: This research explores the use of Fmoc-Ser(tBu)-OH in the synthesis of morpholine derivatives, demonstrating its utility in creating complex molecular structures (Králová et al., 2017). Controlled morphological changes in self-assembled structures formed by Fmoc variants of Threonine and Serine: The study investigates how Fmoc-Ser(tBu)-OH influences the self-assembly of peptides into structured forms, contributing to materials science and nanotechnology (Kshtriya et al., 2021).
• Linkage: Replaces: 04-12-1033
• Analysis Note: Colour (visual): white to off whiteAppearance of substance (visual): powderColour index (0,5 M in DMF): ≤ 150 HazenIdentity (IR): passes testEnantiomeric purity: ≥ 99.8 % (a/a)Purity (HPLC): ≥ 99.0 % (a/a)Fmoc-ß-Ala-OH (HPLC): ≤ 0.1 % (a/a)Fmoc-ß-Ala-Ser (tBu) -OH (HPLC): ≤ 0.1 % (a/a)Fmoc-Ser(tBu)-Ser(tBu)-OH (HPLC): ≤ 0.1 % (a/a)Fmoc-Ser-OH (HPLC): ≤ 0.1 % (a/a)Assay free amino acid (GC): ≤ 0.2 %Purity (TLC(011A)): ≥ 98 %Purity (TLC(0811)): ≥ 98 %Solubility (25 mmole in 50 ml DMF): clearly solubleAssay (acidimetric): ≥ 98.0 %Water (K. F.): ≤ 2.0 %Ethyl acetate (HS-GC): ≤ 0.5 %Acetate (IC): ≤ 0.02 %To see the solvent systems used for TLC of Novabiochem® products please click here.
• Legal Information: Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany