TRIM3/BERP Polyclonal Antibody, Bethyl Laboratories

Description

• The recommended shelf life for this product is 1 year from date of receipt
• Based on 100% sequence identity, this antibody is predicted to react with Mouse, Rat, Bovine, Dog, Horse, Rabbit, Guinea pig_10141, Panda, Orangutan, Monkey, Gorill The protein encoded by this gene is a member of the tripartite motif family, also called the 'RING-B-box-coiled-coil' subgroup of RING finger proteins
• The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region
• This protein localizes to cytoplasmic filaments
• It is similar to a rat protein which is a specific partner for the tail domain of myosin V, a class of myosins which are involved in the targeted transport of organelles
• The rat protein can also interact with alpha-actinin-4
• Thus it is suggested that this human protein may play a role in myosin V-mediated cargo transport
• Alternatively spliced transcript variants encoding the same isoform have been identified.