PIPA146163
DISC1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA146163-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA146163 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
DISC1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
DISC1
Gene Alias
C1orf136; DISC1; disrupted in schizophrenia 1; disrupted in schizophrenia 1 homolog; Disrupted in schizophrenia 1 protein; KIAA0457; RP4-730B13.1; SCZD9
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
244667, 27185, 307940
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
Concentration
1 mg/mL
Formulation
tris glycine with 0.15M NaCl and 0.05% sodium azide
Gene Accession No.
Q810H6, Q811T9, Q9NRI5
Gene Symbols
DISC1
Immunogen
Synthetic peptide made to an internal region (within residues 400-500) of the rat DISC1 protein.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- The theoretical molecular weight of DISC1 is ∽90 kDa
- Due to alternative splicing, DISC1 may also run at ∽75 and 100 kDa
- Suggested positive control: human brain sections (neurons and glia)
- DISC1 (Disrupted in Schizophrenia 1) is a multifunctional protein that interacts with multiple proteins of the centrosome and cytoskeletal system, and is involved in neuronal functions that are dependent upon proper cytoskeletal regulation, including neuronal migration, neurite architecture and intracellular transport
- Regions of the brain which express DISC1 include the hippocampus, lateral septum, amygdala, cerebral cortex, cerebellum and paraventricular hypothalamus, and loss of DISC1 function results in differences in structural organization.The DISC1 gene locus is associated with patients afflicted with schizophrenia as a result of chromosomal translocations
- DISC-1 encodes a large protein predicted to contain a globular N-terminal domain and a helical C-terminal domain, both of which have the potential to form interactions with other proteins
- DISC-1 interacts with proteins involved in the centrosome and cytoskeletal system, including MIPT3, MAP1A and NUDEL; proteins which localize receptors to membranes, including alpha-actinin 2, beta 4-spectrin; and proteins which transduce signals from membrane receptors, including ATF-4 and ATF-5
- Therefore, DISC-1 is thought to be involved in intracellular transport, neurite architecture and/or neuronal migration, all of which are thought to be pathogenic in the schizophrenic brain
- Decreased expression of DISC1 in neurons caused an accelerated rate of neuronal integration, resulting in aberrant morphological development, suggesting that DISC1 plays a role in dendritic development and synapse formation
- DISC-1 is thought to be involved in intracellular transport, neurite architecture and/or neuronal migration, all of which are thought to be pathogenic in the schizophrenic brain.
Compare Similar Items
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Antigen: DISC1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: DISC1
Gene Alias: C1orf136; DISC1; disrupted in schizophrenia 1; disrupted in schizophrenia 1 homolog; Disrupted in schizophrenia 1 protein; KIAA0457; RP4-730B13.1; SCZD9
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 244667, 27185, 307940
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
Concentration: 1 mg/mL
Formulation: tris glycine with 0.15M NaCl and 0.05% sodium azide
Gene Accession No.: Q810H6, Q811T9, Q9NRI5
Gene Symbols: DISC1
Immunogen: Synthetic peptide made to an internal region (within residues 400-500) of the rat DISC1 protein.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
DISC1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
DISC1
Gene Alias:
C1orf136; DISC1; disrupted in schizophrenia 1; disrupted in schizophrenia 1 homolog; Disrupted in schizophrenia 1 protein; KIAA0457; RP4-730B13.1; SCZD9
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
244667, 27185, 307940
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
Concentration:
1 mg/mL
Formulation:
tris glycine with 0.15M NaCl and 0.05% sodium azide
Gene Accession No.:
Q810H6, Q811T9, Q9NRI5
Gene Symbols:
DISC1
Immunogen:
Synthetic peptide made to an internal region (within residues 400-500) of the rat DISC1 protein.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: DISC1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: DISC1
Gene Alias: C1orf136; DISC1; disrupted in schizophrenia 1; disrupted in schizophrenia 1 homolog; Disrupted in schizophrenia 1 protein; KIAA0457; RP4-730B13.1; SCZD9
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 244667, 307940
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
Concentration: 0.95 mg/mL
Formulation: tris glycine with 0.15M NaCl and 0.05% sodium azide
Gene Accession No.: Q810H6, Q811T9
Gene Symbols: DISC1
Immunogen: A synthetic peptide made to an internal region (within residues 700-800) of the mouse DISC1 protein
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
DISC1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
DISC1
Gene Alias:
C1orf136; DISC1; disrupted in schizophrenia 1; disrupted in schizophrenia 1 homolog; Disrupted in schizophrenia 1 protein; KIAA0457; RP4-730B13.1; SCZD9
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
244667, 307940
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
Concentration:
0.95 mg/mL
Formulation:
tris glycine with 0.15M NaCl and 0.05% sodium azide
Gene Accession No.:
Q810H6, Q811T9
Gene Symbols:
DISC1
Immunogen:
A synthetic peptide made to an internal region (within residues 700-800) of the mouse DISC1 protein
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Fe65
Classification: Polyclonal
Conjugate: Unconjugated
Gene: APBB1
Gene Alias: adaptor protein FE65a2; amyloid beta (A4) precursor protein-binding, family B, member 1; amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65); amyloid beta A4 precursor protein-binding family B member 1; amyloid beta precursor protein binding family B member 1; Amyloid-beta A4 precursor protein-binding family B member 1; APBB1; FE65; MGC:9072; Protein Fe65; RIR; stat-like protein
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 11785, 29722, 322
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunoprecipitation, Western Blot
Concentration: 1.3 mg/mL
Formulation: PBS with 15% glycerol and 0.02% sodium azide
Gene Accession No.: O00213, P46933, Q9QXJ1
Gene Symbols: APBB1
Immunogen: Recombinant rat protein expressed in bacteria.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Fe65
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
APBB1
Gene Alias:
adaptor protein FE65a2; amyloid beta (A4) precursor protein-binding, family B, member 1; amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65); amyloid beta A4 precursor protein-binding family B member 1; amyloid beta precursor protein binding family B member 1; Amyloid-beta A4 precursor protein-binding family B member 1; APBB1; FE65; MGC:9072; Protein Fe65; RIR; stat-like protein
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
11785, 29722, 322
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunoprecipitation, Western Blot
Concentration:
1.3 mg/mL
Formulation:
PBS with 15% glycerol and 0.02% sodium azide
Gene Accession No.:
O00213, P46933, Q9QXJ1
Gene Symbols:
APBB1
Immunogen:
Recombinant rat protein expressed in bacteria.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: PGP9.5
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Uchl1
Gene Alias: AW822034; C88048; epididymis luminal protein 117; epididymis secretory protein Li 53; gad; gracile axonal dystrophy; HEL-117; HEL-S-53; MGC133697 protein; NDGOA; neuron cytoplasmic protein 9.5; OTTHUMP00000218137; OTTHUMP00000218139; OTTHUMP00000218140; OTTHUMP00000218141; PARK5; PGP 9.5; PGP9.5; PGP95; protein gene product 9.5; R75593; ubiquitin carboxyl-terminal esterase; ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase); ubiquitin carboxyl-terminal hydrolase isozyme L1; ubiquitin carboxyl-terminal hydrolase L1; ubiquitin carboxy-terminal hydrolase L1; ubiquitin C-terminal hydrolase; ubiquitin C-terminal hydrolase 1; ubiquitin C-terminal hydrolase L1; ubiquitin thioesterase L1; ubiquitin thiolesterase; ubiquitin thiolesterase L1; UCHL; UCHL1; UCH-L1; UCHL-1
Host Species: Rabbit
Purification Method: __
Regulatory Status: RUO
Gene ID (Entrez): 100033838, 22223, 29545, 396637, 514394, 7345, 770302
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: Conc. Not Determined
Formulation: whole serum with 5mM sodium azide
Gene Accession No.: P09936, P23356, Q00981, Q6SEG5, Q9GM50, Q9R0P9
Gene Symbols: Uchl1
Immunogen: Recombinant full length human UCHL1 purified from E. coli.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Bovine, Chicken, Equine, Human, Mouse, Porcine, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
PGP9.5
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Uchl1
Gene Alias:
AW822034; C88048; epididymis luminal protein 117; epididymis secretory protein Li 53; gad; gracile axonal dystrophy; HEL-117; HEL-S-53; MGC133697 protein; NDGOA; neuron cytoplasmic protein 9.5; OTTHUMP00000218137; OTTHUMP00000218139; OTTHUMP00000218140; OTTHUMP00000218141; PARK5; PGP 9.5; PGP9.5; PGP95; protein gene product 9.5; R75593; ubiquitin carboxyl-terminal esterase; ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase); ubiquitin carboxyl-terminal hydrolase isozyme L1; ubiquitin carboxyl-terminal hydrolase L1; ubiquitin carboxy-terminal hydrolase L1; ubiquitin C-terminal hydrolase; ubiquitin C-terminal hydrolase 1; ubiquitin C-terminal hydrolase L1; ubiquitin thioesterase L1; ubiquitin thiolesterase; ubiquitin thiolesterase L1; UCHL; UCHL1; UCH-L1; UCHL-1
Host Species:
Rabbit
Purification Method:
__
Regulatory Status:
RUO
Gene ID (Entrez):
100033838, 22223, 29545, 396637, 514394, 7345, 770302
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
Conc. Not Determined
Formulation:
whole serum with 5mM sodium azide
Gene Accession No.:
P09936, P23356, Q00981, Q6SEG5, Q9GM50, Q9R0P9
Gene Symbols:
Uchl1
Immunogen:
Recombinant full length human UCHL1 purified from E. coli.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Bovine, Chicken, Equine, Human, Mouse, Porcine, Rat
Product Type:
Antibody
Isotype:
IgG