PIPA538436
Phospho-Caspase 9 (Tyr153) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA538436-Each-of-1 | In Stock | ₹ 45,835.00 |
PIPA538436 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,835.00
GST (18%): ₹ 8,250.30
Total Price: ₹ 54,085.30
Antigen
Phospho-Caspase 9 (Tyr153)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
CASP9
Gene Alias
CASP 9, Caspase9, Caspase-9, CASP-9, Apoptotic protease Mch-6, Apoptotic protease-activating factor 3, APAF-3, ICE-like apoptotic protease 6, ICE-LAP6, Caspase-9 subunit p35, Caspase-9 subunit p10, CASP9, MCH6, cas9
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
12371, 58918, 842
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Immunofluorescence, Western Blot
Concentration
1 mg/mL
Formulation
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
P55211, Q8C3Q9
Gene Symbols
CASP9
Immunogen
A synthetic phosphopeptide derived from human Caspase 9 around the phosphorylation site of Tyr153 (L-A-YP-I-L)
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Caspase 9 (ICE-like apoptotic protease 6, ICE LAP6, apoptotic protease Mch6, apoptotic protease activating factor 3, Apaf3) is a member of the peptidase family C14 that contains a CARD domain
- Caspases are cysteine proteases, expressed as inactive precursors, that mediate apoptosis by proteolysis of specific substrates
- Caspase 9 is active as a heterotetramer, is present in the cytosol and, upon activation, translocates to the mitochondria
- Caspase 9 is involved in the caspase activation cascade responsible for apoptosis execution and cleaves/activates Caspase 3 and Caspase 6
- Further, Caspase 9 is involved in the activation cascade of caspases responsible for apoptosis execution
- Binding of caspase-9 to Apaf- 1 leads to activation of the protease which then cleaves and activates caspase-3
- Caspase 9 promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner, and proteolytically cleaves poly(ADP- ribose) polymerase (PARP)
- Caspase 9 is expressed in variety of human tissues
- An isoform of rat Caspase-9 has been identified in which the C terminus of full-length Caspase-9 is replaced with an alternative peptide sequence
- Mutations in Caspase 9 affect brain development
- In mice, insufficient Caspase 9 have resulted in abnormal cerebrum development and neuron development
- In humans, dysfunctional Caspase 9 expression vary from tissue to tissue
- Low levels of Caspase 9 may play a role in cancer development and neurodegenerative diseases such as Alzheimer’s Disease (AD).
Compare Similar Items
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Antigen: Phospho-Caspase 9 (Tyr153)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CASP9
Gene Alias: CASP 9, Caspase9, Caspase-9, CASP-9, Apoptotic protease Mch-6, Apoptotic protease-activating factor 3, APAF-3, ICE-like apoptotic protease 6, ICE-LAP6, Caspase-9 subunit p35, Caspase-9 subunit p10, CASP9, MCH6, cas9
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 12371, 58918, 842
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunofluorescence, Western Blot
Concentration: 1 mg/mL
Formulation: Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: P55211, Q8C3Q9
Gene Symbols: CASP9
Immunogen: A synthetic phosphopeptide derived from human Caspase 9 around the phosphorylation site of Tyr153 (L-A-YP-I-L)
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-Caspase 9 (Tyr153)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CASP9
Gene Alias:
CASP 9, Caspase9, Caspase-9, CASP-9, Apoptotic protease Mch-6, Apoptotic protease-activating factor 3, APAF-3, ICE-like apoptotic protease 6, ICE-LAP6, Caspase-9 subunit p35, Caspase-9 subunit p10, CASP9, MCH6, cas9
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
12371, 58918, 842
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunofluorescence, Western Blot
Concentration:
1 mg/mL
Formulation:
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
P55211, Q8C3Q9
Gene Symbols:
CASP9
Immunogen:
A synthetic phosphopeptide derived from human Caspase 9 around the phosphorylation site of Tyr153 (L-A-YP-I-L)
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-Caspase 9 (Ser144)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CASP9
Gene Alias: CASP 9, Caspase9, Caspase-9, CASP-9, Apoptotic protease Mch-6, Apoptotic protease-activating factor 3, APAF-3, ICE-like apoptotic protease 6, ICE-LAP6, Caspase-9 subunit p35, Caspase-9 subunit p10, CASP9, MCH6, cas9
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 842
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: P55211
Gene Symbols: CASP9
Immunogen: A synthetic phosphopeptide derived from human Caspase 9 around the phosphorylation site of Ser144 (L-E-SP-L-R)
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-Caspase 9 (Ser144)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CASP9
Gene Alias:
CASP 9, Caspase9, Caspase-9, CASP-9, Apoptotic protease Mch-6, Apoptotic protease-activating factor 3, APAF-3, ICE-like apoptotic protease 6, ICE-LAP6, Caspase-9 subunit p35, Caspase-9 subunit p10, CASP9, MCH6, cas9
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
842
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
P55211
Gene Symbols:
CASP9
Immunogen:
A synthetic phosphopeptide derived from human Caspase 9 around the phosphorylation site of Ser144 (L-E-SP-L-R)
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-Caspase 3 (Ser150)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CASP3
Gene Alias: Caspase-3, Caspase3, CASP-3, Apopain, Cysteine protease CPP32, CPP-32, Protein Yama, SREBP cleavage activity 1, SCA-1, CASP3, CPP32
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 12367, 25402, 836
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: P42574, P70677, P55213
Gene Symbols: CASP3
Immunogen: A synthetic phosphopeptide derived from human Caspase 3 around the phosphorylation site of Ser150 (C-R-SP-L-T)
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-Caspase 3 (Ser150)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CASP3
Gene Alias:
Caspase-3, Caspase3, CASP-3, Apopain, Cysteine protease CPP32, CPP-32, Protein Yama, SREBP cleavage activity 1, SCA-1, CASP3, CPP32
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
12367, 25402, 836
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
P42574, P70677, P55213
Gene Symbols:
CASP3
Immunogen:
A synthetic phosphopeptide derived from human Caspase 3 around the phosphorylation site of Ser150 (C-R-SP-L-T)
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-Catalase (Tyr385)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CAT
Gene Alias: CAT
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 12359, 24248, 847
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: P04040, P24270, P04762
Gene Symbols: CAT
Immunogen: A synthetic phosphopeptide derived from human Catalase around the phosphorylation site of Tyr385 (A-N-YP-Q-R)
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-Catalase (Tyr385)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CAT
Gene Alias:
CAT
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
12359, 24248, 847
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
P04040, P24270, P04762
Gene Symbols:
CAT
Immunogen:
A synthetic phosphopeptide derived from human Catalase around the phosphorylation site of Tyr385 (A-N-YP-Q-R)
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG