IBX polystyrene

Description

• General description: This polymer-bound version of IBX cleanly converts primary and secondary alcohols to the corresponding aldehydes and ketones [1,2]. It is particularly useful for the synthesis of peptide aldehydes as it oxidises peptide alcohols efficiently and spent resin can be simply removed by filtration.Literature references[1] G. Sorg, et al. (2001) Angew. Chem. Int. Ed., 40, 4395. [2] G. Sorg, et al. (2005) J. Pept. Sci.,11, 147.
• Application: 2-Iodoxybenzoic Acid: An Oxidant for Functional Group Transformations: This study discusses the use of IBX for various organic transformations, including the oxidation of silyl enol ethers and the preparation of polystyrene supported periodinane reagent. (Nair, 2020).
• Linkage: Replaces: 01-64-0445
• Analysis Note: Color (visual): white to yellow to beigeAppearance of substance (visual): beadsLoading (determined by elemental analysis of iodine): 0.90 - 1.50 mmol/gOxidation of Cinnamyl alcohol to Cinnamaldehyde (2 eq. IBX PS): ≥ 90 %Swelling Volume (in DMF): lot specific resultThe polymer matrix is copoly (styrene - 1% DVB) 200 -400 mesh.
• Legal Information: Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany