Description

• Application: Effect of salt modulators on the elution behavior of insulin and the separation of product-related impurities in reversed-phase chromatography.: The study examines how potassium sulfate and other salts affect the chromatography process, specifically focusing on insulin purification. The results are crucial for optimizing chromatographic methods in pharmaceutical production (Koch et al., 2023).
• Analysis Note: Purity (metallic): ≥ 99.999 %Assay (alkalimetric): ≥ 99.0Chloride (Cl): ≤ 5 ppmTotal nitrogen (N): ≤ 5.0 ppmAl (Aluminium): ≤ 0.050 ppmBa (Barium): ≤ 1.0 ppmBi (Bismuth): ≤ 0.01 ppmCa (Calcium): ≤ 0.10 ppmCd (Cadmium): ≤ 0.005 ppmCe (Cerium): ≤ 0.020 ppmCo (Cobalt): ≤ 0.005 ppmCr (Chromium): ≤ 0.010 ppmCu (Copper): ≤ 0.020 ppmEu (Europium): ≤ 0.010 ppmFe (Iron): ≤ 0.050 ppmHg (Mercury): ≤ 0.05 ppmLa (Lanthanum): ≤ 0.010 ppmLi (Lithium): ≤ 0.2 ppmMg (Magnesium): ≤ 0.10 ppmMn (Manganese): ≤ 0.020 ppmNa (Sodium): ≤ 5.0 ppmNi (Nickel): ≤ 0.020 ppmPb (Lead): ≤ 0.050 ppmSc (Scandium): ≤ 0.010 ppmSm (Samarium): ≤ 0.010 ppmSr (Strontium): ≤ 0.10 ppmTl (Thallium): ≤ 0.01 ppmY (Yttrium): ≤ 0.010 ppmYb (Ytterbium): ≤ 0.010 ppmZn (Zinc): ≤ 0.050 ppm
• Legal Information: SUPRAPUR is a registered trademark of Merck KGaA, Darmstadt, Germany